Pizza Club

Date/Time
Date(s) - 28/11/2024
5:30 pm - 7:00 pm

Location
BT2 Détente / Kitchenette 1st Floor room 101

Categories


Do you like scientific discussion? And how about Pizza?

If we gained your attention with ‘scientific’, or at least with ‘Pizza’, then you are already looking forward to the right event!

Pizza Club is a regularly held Journal Club event co-organized by The Representatives of the Doctoral Programme in Systems and Molecular Biomedicine, part of the Doctoral School in Science and Engineering (DSSE); and the Uni.lu student association ISCB RSG Luxembourg.

In short, Students (PhD candidates) present a scientific paper (+- 20 mins) they find interesting or that inspired the development of their individual PhD project (doesn’t need to be authored by the speaker).

There will be a open discussion round after each scientific presentation (2-3 students per event), followed by informal and fun chatting with some pizzas around!

Moreover, each presentation of peer-reviewed papers will be rewarded by 0.5 ECTS!


Bio: Lena is a second year PhD student in the Systems Ecology group led by Prof. Paul Wilmes at the University of Luxembourg. She’s combining patient-derived intestinal organoids and gut-on-chip technology to study the molecular mechanisms of host-microbe interactions in the colon.

Paper : Paper presented: Bioengineered human colon organoids with in vivo-like cellular complexity and function (https://doi.org/10.1016/j.stem.2024.05.007)

Paper description: The paper describes a new advanced in vitromodel of the gut called “mini-colons” which integrates organoids and gut-on-chip technology. The model recapitulates the spatial organization, cellular composition, and function of the colon. The utility of this model as a preclinical assessment of drug safety is demonstrated by the characterization of differential toxicity profiles of anticancer drugs.

Bio: Victoria is a second year PhD Student in the Cardiovascular research Unit at the Luxembourg Institute of Health, under the supervision of Dr. Yvan Devaux. Her PhD project is focusing on the RNA modification, called m6A, in cardiac arrest and the neurological outcome.

Paper: A novel RT-qPCR based assay for the relative quantification of residue specific m6A methylation : https://www.nature.com/articles/s41598-019-40018-6

Paper description: The paper described a new method, a RT-qPCR model improved to quantify m6A methylation. The method is cost effective and allows to simplify validation of m6A sites detected by sequencing technics. They have also validated their methods in different models.


If we attracted your interest by now, feel free to join the monthly Pizza Club, either as part of Audience or as a registered Speaker. For the latter, please kindly use this form to sign up as an upcoming Speaker, by choosing your category of paper and desired month to present. Looking forward to seeing you at the next Pizza Club!